Associate Professor Anoop Enjeti
(MBBS, MD, FRCP (UK), FRCPA, FACP, FASCP, MClin Epid (Mol Genetics), GradCert Bioethics, PhD
Senior Staff Specialist Haematologist/Conjoint Associate Professor University of Newcastle)

DepartmentHaematology
Research AreasHaematological Malignancies, Translational Diagnostics, Microvesicles, Health System Changes
Research TopicsLeukaemia - drug development and diagnostics, Haematological Genomics, Thrombosis, Transfusion Science
Research TypesClinical Trials, Laboratory Research

Conjoint Associate Professor Anoop Enjeti is a clinician researcher conducting clinical trials and laboratory-based research at Calvary Mater Newcastle. He also leads the Translational Haematology Research Program, a collaboration involving the Calvary Mater Newcastle, University of Newcastle, Hunter Cancer Research Alliance and NSW Health Pathology.

As the clinical lead for leukemia and myelodysplasia (pre-leukemia) clinical trials (including for the Australasian Leukemia and Lymphoma Group, where he is developing a national platform trial concept), Dr Enjeti has been integrally involved in more than 30 trials. One trial resulted in the use of Venotoclax as an oral anti-leukemic drug, which the US Food and Drug Administration now considers as being breakthrough therapy in older acute myeloid leukemia patients.

His translational haematology research program links discovery, diagnostics, health system changes and early phase clinical trials to improve the outcomes for patients in regional Australia and beyond. He also works closely with colleagues to develop novel therapeutic strategies in myeloid leukaemia.

Dr Enjeti is the Director of Haematology Division (NSW Health Pathology for Hunter New England and Mid North Coast Local Health Districts) and chief examiner of haematology for the Royal College of Pathologists of Australia. He has more than 43 publications and has obtained more than $3million in competitive and other research funding, including a recent National Health and Medical Research Council Ideas grant.

Further information on Dr Enjeti’s research grants and supervision is available here, along with a list of his publications.

Getting to know you

When did you start doing research?

My first research was about geographic, ethnic and genetic heterogeneity in acute myeloid leukemia undertaken in Singapore General Hospital, which resulted in a high impact publication.

What is your most significant contribution to research?

Recent work investigating the role of miRNA carried within microvesicles in a pre-leukemic state condition known as myelodysplasia has produced some very exciting results.

What research achievement are you most proud of?

Seeing the research work being published and establishing collaborative research networks with the Leukemia Research Group in Newcastle has been fantastic.

What inspires you?

The sense of collaborative and scientific principles involved in research.

What did you do before coming to work at the Calvary Mater Newcastle?

I was a clinical associate in Haematology at Singapore General Hospital.

What did you do before you became a researcher?

I was an advanced trainee in haematology, completing my clinical training.

What made you decide to do research?

In 2000, my thesis on gastric cancers won an award for the best oral abstract award. This made me realise that a career as a clinician researcher was a real possibility early in my career.

What was your first/worst/best/strangest/memorable/ job in research?

My most memorable moment was getting my first PhD student to finish her manuscript and submit it for publication.

What do you do to relax?

I cycle, listen to classical music with my wife, and play in the yard with my two boys.

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